TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy

Activation of fibroblasts is essential for physiological tissue repair. Uncontrolled activation of fibroblasts, however, may lead to tissue fibrosis with organ dysfunction. Although several pathways capable of promoting fibroblast activation and tissue repair have been identified, their interplay in...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zehender, Ariella, Li, Yi-Nan, Lin, Neng-Yu, Stefanica, Adrian, Nüchel, Julian, Chen, Chih-Wei, Hsu, Hsiao-Han, Zhu, Honglin, Ding, Xiao, Huang, Jingang, Shen, Lichong, Györfi, Andrea-Hermina, Soare, Alina, Rauber, Simon, Bergmann, Christina, Ramming, Andreas, Plomann, Markus, Eckes, Beate, Schett, Georg, Distler, Jörg H. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292318/
https://ncbi.nlm.nih.gov/pubmed/34285225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24601-y
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