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Transcription factor Zhx2 restricts NK cell maturation and suppresses their antitumor immunity
The maturation and functional competence of natural killer (NK) cells is a tightly controlled process that relies on transcription factors (TFs). Here, we identify transcriptional repressor zinc fingers and homeoboxes 2 (Zhx2) as a novel regulator that restricts NK cell maturation and function. Mice...
में बचाया:
| में प्रकाशित: | J Exp Med |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Rockefeller University Press
2021
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8292132/ https://ncbi.nlm.nih.gov/pubmed/34279541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20210009 |
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