Tumor suppressor ZHX2 inhibits NAFLD–HCC progression via blocking LPL-mediated lipid uptake

Non-alcoholic fatty liver disease (NAFLD) leads to hepatocellular carcinoma (HCC). However, the underlying mechanism remains largely unclear. Here, we investigated the role of the tumor suppressor Zinc fingers and homeoboxes 2 (ZHX2) in the progression of NAFLD to HCC. ZHX2 expression was significan...

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Pubblicato in:Cell Death Differ
Autori principali: Wu, Zhuanchang, Ma, Hongxin, Wang, Liyuan, Song, Xiaojia, Zhang, Jie, Liu, Wen, Ge, Yutong, Sun, Yang, Yu, Xiangguo, Wang, Zehua, Wang, Jianping, Zhang, Yankun, Li, Chunyang, Li, Nailin, Gao, Lifen, Liang, Xiaohong, Yue, Xuetian, Ma, Chunhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206072/
https://ncbi.nlm.nih.gov/pubmed/31740790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0453-z
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