Transcription factor Zhx2 restricts NK cell maturation and suppresses their antitumor immunity

The maturation and functional competence of natural killer (NK) cells is a tightly controlled process that relies on transcription factors (TFs). Here, we identify transcriptional repressor zinc fingers and homeoboxes 2 (Zhx2) as a novel regulator that restricts NK cell maturation and function. Mice...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Tan, Siyu, Guo, Xiaowei, Li, Mengzhen, Wang, Tixiao, Wang, Zehua, Li, Chunyang, Wu, Zhuanchang, Li, Nailin, Gao, Lifen, Liang, Xiaohong, Ma, Chunhong
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292132/
https://ncbi.nlm.nih.gov/pubmed/34279541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20210009
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki