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TNF stimulation primarily modulates transcriptional burst size of NF‐κB‐regulated genes
Cell‐to‐cell heterogeneity is a feature of the tumor necrosis factor (TNF)‐stimulated inflammatory response mediated by the transcription factor NF‐κB, motivating an exploration of the underlying sources of this noise. Here, we combined single‐transcript measurements with computational models to stu...
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| Publicado no: | Mol Syst Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8290835/ https://ncbi.nlm.nih.gov/pubmed/34288498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.202010127 |
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