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Expanding the Role of STING in Cellular Homeostasis and Transformation
The cytosolic DNA-sensing cGAS–STING pathway was originally characterized as a key innate immune mediator responsible for the induction of antiviral genes in response to foreign DNA species in the cytosol. Mounting evidence, however, points to a complex role for cGAS and STING in cancer. Two recent...
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| Publicado no: | Trends Cancer |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8290631/ https://ncbi.nlm.nih.gov/pubmed/30961826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2019.02.001 |
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