Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway

Acquired heterotopic ossification (HO) is the extraskeletal bone formation after trauma. Various mesenchymal progenitors are reported to participate in ectopic bone formation. Here we induce acquired HO in mice by Achilles tenotomy and observe that conditional knockout (cKO) of fibroblast growth fac...

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Pubblicato in:Nat Commun
Autori principali: Zhang, Dali, Huang, Junlan, Sun, Xianding, Chen, Hangang, Huang, Shuo, Yang, Jing, Du, Xiaolan, Tan, Qiaoyan, Luo, Fengtao, Zhang, Ruobin, Zhou, Siru, Jiang, Wanling, Ni, Zhenhong, Wang, Zuqiang, Jin, Min, Xu, Meng, Li, Fangfang, Chen, Liang, Liu, Mi, Su, Nan, Luo, Xiaoqing, Yin, Liangjun, Zhu, Ying, Feng, Jerry Q., Chen, Di, Qi, Huabing, Chen, Lin, Xie, Yangli
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289847/
https://ncbi.nlm.nih.gov/pubmed/34282140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24643-2
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