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Trehalose Augments Neuron Survival and Improves Recovery from Spinal Cord Injury via mTOR-Independent Activation of Autophagy

Spinal cord injury (SCI) is a major cause of irreversible nerve injury and leads to serious tissue loss and neurological dysfunction. Thorough investigation of cellular mechanisms, such as autophagy, is crucial for developing novel and effective therapeutics. We administered trehalose, an mTOR-indep...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Zhou, Kailiang, Chen, Huanwen, Xu, Huazi, Jia, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289614/
https://ncbi.nlm.nih.gov/pubmed/34336117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8898996
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