Involvement of mTOR Pathways in Recovery from Spinal Cord Injury by Modulation of Autophagy and Immune Response

Traumatic spinal cord injury (SCI) is untreatable and remains the leading cause of disability. Neuroprotection and recovery after SCI can be partially achieved by rapamycin (RAPA) treatment, an inhibitor of mTORC1, complex 1 of the mammalian target of rapamycin (mTOR) pathway. However, mechanisms re...

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Veröffentlicht in:Biomedicines
Hauptverfasser: Vargova, Ingrid, Machova Urdzikova, Lucia, Karova, Kristyna, Smejkalova, Barbora, Sursal, Tolga, Cimermanova, Veronika, Turnovcova, Karolina, Gandhi, Chirag D., Jhanwar-Uniyal, Meena, Jendelova, Pavla
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225190/
https://ncbi.nlm.nih.gov/pubmed/34073791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9060593
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