Involvement of mTOR Pathways in Recovery from Spinal Cord Injury by Modulation of Autophagy and Immune Response

Traumatic spinal cord injury (SCI) is untreatable and remains the leading cause of disability. Neuroprotection and recovery after SCI can be partially achieved by rapamycin (RAPA) treatment, an inhibitor of mTORC1, complex 1 of the mammalian target of rapamycin (mTOR) pathway. However, mechanisms re...

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Pubblicato in:Biomedicines
Autori principali: Vargova, Ingrid, Machova Urdzikova, Lucia, Karova, Kristyna, Smejkalova, Barbora, Sursal, Tolga, Cimermanova, Veronika, Turnovcova, Karolina, Gandhi, Chirag D., Jhanwar-Uniyal, Meena, Jendelova, Pavla
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225190/
https://ncbi.nlm.nih.gov/pubmed/34073791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9060593
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