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Transplantation of neural precursors generated from spinal progenitor cells reduces inflammation in spinal cord injury via NF-κB pathway inhibition

BACKGROUND: Traumatic spinal cord injury (SCI) triggers a chain of events that is accompanied by an inflammatory reaction leading to necrotic cell death at the core of the injury site, which is restricted by astrogliosis and apoptotic cell death in the surrounding areas. Activation of nuclear factor...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Karova, Kristyna, Wainwright, John V., Machova-Urdzikova, Lucia, Pisal, Rishikaysh V., Schmidt, Meic, Jendelova, Pavla, Jhanwar-Uniyal, Meena
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335809/
https://ncbi.nlm.nih.gov/pubmed/30654804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1394-7
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