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Transplantation of neural precursors generated from spinal progenitor cells reduces inflammation in spinal cord injury via NF-κB pathway inhibition

BACKGROUND: Traumatic spinal cord injury (SCI) triggers a chain of events that is accompanied by an inflammatory reaction leading to necrotic cell death at the core of the injury site, which is restricted by astrogliosis and apoptotic cell death in the surrounding areas. Activation of nuclear factor...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Karova, Kristyna, Wainwright, John V., Machova-Urdzikova, Lucia, Pisal, Rishikaysh V., Schmidt, Meic, Jendelova, Pavla, Jhanwar-Uniyal, Meena
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335809/
https://ncbi.nlm.nih.gov/pubmed/30654804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1394-7
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