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GeneReg: a constraint-based approach for design of feasible metabolic engineering strategies at the gene level

MOTIVATION: Large-scale metabolic models are widely used to design metabolic engineering strategies for diverse biotechnological applications. However, the existing computational approaches focus on alteration of reaction fluxes and often neglect the manipulations of gene expression to implement the...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Razaghi-Moghadam, Zahra, Nikoloski, Zoran
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289378/
https://ncbi.nlm.nih.gov/pubmed/33245091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa996
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