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GeneReg: a constraint-based approach for design of feasible metabolic engineering strategies at the gene level

MOTIVATION: Large-scale metabolic models are widely used to design metabolic engineering strategies for diverse biotechnological applications. However, the existing computational approaches focus on alteration of reaction fluxes and often neglect the manipulations of gene expression to implement the...

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Bibliografski detalji
Izdano u:Bioinformatics
Glavni autori: Razaghi-Moghadam, Zahra, Nikoloski, Zoran
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289378/
https://ncbi.nlm.nih.gov/pubmed/33245091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa996
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