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GeneReg: a constraint-based approach for design of feasible metabolic engineering strategies at the gene level

MOTIVATION: Large-scale metabolic models are widely used to design metabolic engineering strategies for diverse biotechnological applications. However, the existing computational approaches focus on alteration of reaction fluxes and often neglect the manipulations of gene expression to implement the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioinformatics
Prif Awduron: Razaghi-Moghadam, Zahra, Nikoloski, Zoran
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289378/
https://ncbi.nlm.nih.gov/pubmed/33245091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa996
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