Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human Induced Pluripotent Stem Cells

Human cerebral organoid (CO) is a three-dimensional (3D) cell culture system that recapitulates the developing human brain. While CO has proved an invaluable tool for studying neurological disorders in a more clinically relevant matter, there have still been several shortcomings including CO variabi...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Bodnar, Brittany, Zhang, Yongang, Liu, Jinbiao, Lin, Yuan, Wang, Peng, Wei, Zhengyu, Saribas, Sami, Zhu, Yuanjun, Li, Fang, Wang, Xu, Yang, Wenli, Li, Qingsheng, Ho, Wen-Zhe, Hu, Wenhui
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cellular Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8288463/
https://ncbi.nlm.nih.gov/pubmed/34290591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.682272
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