Microglia innately develop within cerebral organoids

Cerebral organoids are 3D stem cell-derived models that can be utilized to study the human brain. The current consensus is that cerebral organoids consist of cells derived from the neuroectodermal lineage. This limits their value and applicability, as mesodermal-derived microglia are important playe...

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Vydáno v:Nat Commun
Hlavní autoři: Ormel, Paul R., Vieira de Sá, Renata, van Bodegraven, Emma J., Karst, Henk, Harschnitz, Oliver, Sneeboer, Marjolein A. M., Johansen, Lill Eva, van Dijk, Roland E., Scheefhals, Nicky, Berdenis van Berlekom, Amber, Ribes Martínez, Eduardo, Kling, Sandra, MacGillavry, Harold D., van den Berg, Leonard H., Kahn, René S., Hol, Elly M., de Witte, Lot D., Pasterkamp, R. Jeroen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177485/
https://ncbi.nlm.nih.gov/pubmed/30301888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06684-2
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