Microglia innately develop within cerebral organoids

Cerebral organoids are 3D stem cell-derived models that can be utilized to study the human brain. The current consensus is that cerebral organoids consist of cells derived from the neuroectodermal lineage. This limits their value and applicability, as mesodermal-derived microglia are important playe...

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Publicado en:Nat Commun
Main Authors: Ormel, Paul R., Vieira de Sá, Renata, van Bodegraven, Emma J., Karst, Henk, Harschnitz, Oliver, Sneeboer, Marjolein A. M., Johansen, Lill Eva, van Dijk, Roland E., Scheefhals, Nicky, Berdenis van Berlekom, Amber, Ribes Martínez, Eduardo, Kling, Sandra, MacGillavry, Harold D., van den Berg, Leonard H., Kahn, René S., Hol, Elly M., de Witte, Lot D., Pasterkamp, R. Jeroen
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177485/
https://ncbi.nlm.nih.gov/pubmed/30301888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06684-2
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