Combinatorial analysis of translation dynamics reveals eIF2 dependence of translation initiation at near-cognate codons

Although ribosome-profiling and translation initiation sequencing (TI-seq) analyses have identified many noncanonical initiation codons, the precise detection of translation initiation sites (TISs) remains a challenge, mainly because of experimental artifacts of such analyses. Here, we describe a ne...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Ichihara, Kazuya, Matsumoto, Akinobu, Nishida, Hiroshi, Kito, Yuki, Shimizu, Hideyuki, Shichino, Yuichi, Iwasaki, Shintaro, Imami, Koshi, Ishihama, Yasushi, Nakayama, Keiichi I
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Computational Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287933/
https://ncbi.nlm.nih.gov/pubmed/34226921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab549
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