The synaptonemal complex central region modulates crossover pathways and feedback control of meiotic double-strand break formation

The synaptonemal complex (SC) is a proteinaceous structure that mediates homolog engagement and genetic recombination during meiosis. In budding yeast, Zip-Mer-Msh (ZMM) proteins promote crossover (CO) formation and initiate SC formation. During SC elongation, the SUMOylated SC component Ecm11 and t...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Lee, Min-Su, Higashide, Mika T, Choi, Hyungseok, Li, Ke, Hong, Soogil, Lee, Kangseok, Shinohara, Akira, Shinohara, Miki, Kim, Keun P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
Genome Integrity, Repair and Replication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287913/
https://ncbi.nlm.nih.gov/pubmed/34197600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab566
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