SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction

The multidomain non-structural protein 3 (Nsp3) is the largest protein encoded by coronavirus (CoV) genomes and several regions of this protein are essential for viral replication. Of note, SARS-CoV Nsp3 contains a SARS-Unique Domain (SUD), which can bind Guanine-rich non-canonical nucleic acid stru...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Lavigne, Marc, Helynck, Olivier, Rigolet, Pascal, Boudria-Souilah, Rofia, Nowakowski, Mireille, Baron, Bruno, Brülé, Sébastien, Hoos, Sylviane, Raynal, Bertrand, Guittat, Lionel, Beauvineau, Claire, Petres, Stéphane, Granzhan, Anton, Guillon, Jean, Pratviel, Geneviève, Teulade-Fichou, Marie-Paule, England, Patrick, Mergny, Jean-Louis, Munier-Lehmann, Hélène
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287907/
https://ncbi.nlm.nih.gov/pubmed/34232992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab571
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados