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“One Ring to Bind Them All”—Part I: The Efficiency of the Macrocyclic Scaffold for G-Quadruplex DNA Recognition

Macrocyclic scaffolds are particularly attractive for designing selective G-quadruplex ligands essentially because, on one hand, they show a poor affinity for the “standard” B-DNA conformation and, on the other hand, they fit nicely with the external G-quartets of quadruplexes. Stimulated by the pio...

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Detalhes bibliográficos
Main Authors: Monchaud, David, Granzhan, Anton, Saettel, Nicolas, Guédin, Aurore, Mergny, Jean-Louis, Teulade-Fichou, Marie-Paule
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915875/
https://ncbi.nlm.nih.gov/pubmed/20725629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/525862
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