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p53-intact cancers escape tumor suppression through loss of long noncoding RNA Dino
Many long noncoding RNA (lncRNA) genes exist near cancer-associated loci, yet evidence connecting lncRNA functions to recurrent genetic alterations in cancer are lacking. Here, we report that DINO, the lncRNA transcribed from the cancer-associated DINO/CDKN1A locus, suppresses tumor formation indepe...
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| Pubblicato in: | Cell Rep |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8287872/ https://ncbi.nlm.nih.gov/pubmed/34192538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109329 |
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