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Unlocking the potential of antibody–drug conjugates for cancer therapy

Nine different antibody–drug conjugates (ADCs) are currently approved as cancer treatments, with dozens more in preclinical and clinical development. The primary goal of ADCs is to improve the therapeutic index of antineoplastic agents by restricting their systemic delivery to cells that express the...

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Detalhes bibliográficos
Publicado no:Nat Rev Clin Oncol
Main Authors: Drago, Joshua Z., Modi, Shanu, Chandarlapaty, Sarat
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287784/
https://ncbi.nlm.nih.gov/pubmed/33558752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41571-021-00470-8
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