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Unlocking the potential of antibody–drug conjugates for cancer therapy

Nine different antibody–drug conjugates (ADCs) are currently approved as cancer treatments, with dozens more in preclinical and clinical development. The primary goal of ADCs is to improve the therapeutic index of antineoplastic agents by restricting their systemic delivery to cells that express the...

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Bibliografski detalji
Izdano u:Nat Rev Clin Oncol
Glavni autori: Drago, Joshua Z., Modi, Shanu, Chandarlapaty, Sarat
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287784/
https://ncbi.nlm.nih.gov/pubmed/33558752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41571-021-00470-8
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