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Unlocking the potential of antibody–drug conjugates for cancer therapy

Nine different antibody–drug conjugates (ADCs) are currently approved as cancer treatments, with dozens more in preclinical and clinical development. The primary goal of ADCs is to improve the therapeutic index of antineoplastic agents by restricting their systemic delivery to cells that express the...

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Библиографические подробности
Опубликовано в: :Nat Rev Clin Oncol
Главные авторы: Drago, Joshua Z., Modi, Shanu, Chandarlapaty, Sarat
Формат: Artigo
Язык:Inglês
Опубликовано: 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287784/
https://ncbi.nlm.nih.gov/pubmed/33558752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41571-021-00470-8
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