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Unlocking the potential of antibody–drug conjugates for cancer therapy

Nine different antibody–drug conjugates (ADCs) are currently approved as cancer treatments, with dozens more in preclinical and clinical development. The primary goal of ADCs is to improve the therapeutic index of antineoplastic agents by restricting their systemic delivery to cells that express the...

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Bibliografiska uppgifter
I publikationen:Nat Rev Clin Oncol
Huvudupphovsmän: Drago, Joshua Z., Modi, Shanu, Chandarlapaty, Sarat
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287784/
https://ncbi.nlm.nih.gov/pubmed/33558752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41571-021-00470-8
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