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CARs of the future

CAR T cells have revolutionized the treatment of relapsed and refractory CD19-positive leukemia and lymphoma. Unfortunately, the majority of patients treated will not achieve durable remissions. Reasons for these suboptimal clinical outcomes can be tied back to intrinsic CAR T cell design and manufa...

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Detalles Bibliográficos
Publicado en:Am J Hematol
Main Authors: Daniyan, Anthony F., Brentjens, Renier J.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287577/
https://ncbi.nlm.nih.gov/pubmed/30680777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25416
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