Pharmacokinetics and Biologic Activity of Apixaban in Healthy Dogs

Thrombosis is common in critically ill dogs and causes considerable morbidity and mortality. The direct factor Xa inhibitor apixaban is safe, efficacious, and convenient in humans. This study aimed to determine the pharmacokinetics (PK), bioactivity, protein binding, and bioavailability of apixaban...

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發表在:Front Vet Sci
Main Authors: Herrera, Noelle D., Birschmann, Ingvild, Wolny, Monika, Papich, Mark G., Brooks, Marjory B., Goggs, Robert
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2021
主題:
Veterinary Science
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287028/
https://ncbi.nlm.nih.gov/pubmed/34291105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fvets.2021.702821
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