Pharmacokinetics and Biologic Activity of Apixaban in Healthy Dogs

Thrombosis is common in critically ill dogs and causes considerable morbidity and mortality. The direct factor Xa inhibitor apixaban is safe, efficacious, and convenient in humans. This study aimed to determine the pharmacokinetics (PK), bioactivity, protein binding, and bioavailability of apixaban...

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Publicat a:Front Vet Sci
Autors principals: Herrera, Noelle D., Birschmann, Ingvild, Wolny, Monika, Papich, Mark G., Brooks, Marjory B., Goggs, Robert
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Veterinary Science
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287028/
https://ncbi.nlm.nih.gov/pubmed/34291105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fvets.2021.702821
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