Pharmacokinetics and Biologic Activity of Apixaban in Healthy Dogs

Thrombosis is common in critically ill dogs and causes considerable morbidity and mortality. The direct factor Xa inhibitor apixaban is safe, efficacious, and convenient in humans. This study aimed to determine the pharmacokinetics (PK), bioactivity, protein binding, and bioavailability of apixaban...

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Detalhes bibliográficos
Publicado no:Front Vet Sci
Main Authors: Herrera, Noelle D., Birschmann, Ingvild, Wolny, Monika, Papich, Mark G., Brooks, Marjory B., Goggs, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Veterinary Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287028/
https://ncbi.nlm.nih.gov/pubmed/34291105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fvets.2021.702821
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