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P63 deficiency and CDX2 overexpression lead to Barrett’s-like metaplasia in mouse esophageal epithelium

BACKGROUND: The cellular origin and molecular mechanisms of Barrett’s esophagus (BE) are still controversial. Transdifferentiation is a mechanism characterized by activation of the intestinal differentiation program and inactivation of the squamous differentiation program. AIMS: Renal capsule grafti...

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Detalhes bibliográficos
Publicado no:Dig Dis Sci
Main Authors: Fang, Yu, Li, Wenbo, Chen, Xiaoxin
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286978/
https://ncbi.nlm.nih.gov/pubmed/33469811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-020-06756-8
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