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Nrf2 deficiency impairs the barrier function of mouse esophageal epithelium

OBJECTIVE: As a major cellular defense mechanism, the Nrf2/Keap1 pathway regulates expression of genes involved in detoxification and stress response. Our previous study revealed activation of the Nrf2/Keap1 pathway at the maturation phase during mouse esophageal development, suggesting a potential...

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Detalhes bibliográficos
Main Authors: Chen, Hao, Hu, Yuhui, Fang, Yu, Djukic, Zorka, Yamamoto, Masayuki, Shaheen, Nicholas J., Orlando, Roy C., Chen, Xiaoxin
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883925/
https://ncbi.nlm.nih.gov/pubmed/23676441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-303731
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