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Differential Inhibition of Equilibrative Nucleoside Transporter 1 (ENT1) Activity by Tyrosine Kinase Inhibitors

BACKGROUND AND OBJECTIVES: Equilibrative nucleoside transporter (ENT) 1 is a widely-expressed drug transporter, handling nucleoside analogues as well as endogenous nucleosides. ENT1 has been postulated to be inhibited by some marketed tyrosine kinase inhibitors (TKIs). To obtain insights into this p...

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Vydáno v:Eur J Drug Metab Pharmacokinet
Hlavní autoři: Jouan, Elodie, Moreau, Amélie, Bruyere, Arnaud, Alim, Karima, Denizot, Claire, Parmentier, Yannick, Fardel, Olivier
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286641/
https://ncbi.nlm.nih.gov/pubmed/34275128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-021-00703-2
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