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Fine sampling of sequence space for membrane protein structural biology
We describe an enhancement of traditional genomics-based approaches to improve the success of structure determination of membrane proteins. Following a broad screen of sequence space to identify initial expression-positive targets, we employ a second step to select orthologs with closely related seq...
שמור ב:
| הוצא לאור ב: | J Mol Biol |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8286341/ https://ncbi.nlm.nih.gov/pubmed/34022208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2021.167055 |
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