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Fine sampling of sequence space for membrane protein structural biology

We describe an enhancement of traditional genomics-based approaches to improve the success of structure determination of membrane proteins. Following a broad screen of sequence space to identify initial expression-positive targets, we employ a second step to select orthologs with closely related seq...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Loukeris, Michael, Sanghai, Zahra Assur, Vendome, Jeremie, Hendrickson, Wayne A., Kloss, Brian, Mancia, Filippo
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286341/
https://ncbi.nlm.nih.gov/pubmed/34022208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2021.167055
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