Chemoproteomic study uncovers HemK2/KMT9 as a new target for NTMT1 bisubstrate inhibitors

Lignende værker

• Human HemK2/KMT9/N6AMT1 is an active protein methyltransferase, but does not act on DNA in vitro, in the presence of Trm112
  af: Woodcock, Clayton B., et al.
  Udgivet: (2019)
• Discovery of Bisubstrate Inhibitors for Protein N‑Terminal Methyltransferase 1
  af: Chen, Dongxing, et al.
  Udgivet: (2019)
• Structural Characterization and Comparative Phylogenetic Analysis of Escherichia coli HemK, a Protein (N5)-glutamine Methyltransferase
  af: Yang, Zhe, et al.
  Udgivet: (2004)
• HemK, a class of protein methyl transferase with similarity to DNA methyl transferases, methylates polypeptide chain release factors, and hemK knockout induces defects in translational termination
  af: Nakahigashi, Kenji, et al.
  Udgivet: (2002)
• Probing the Plasticity in the Active Site of Protein N-terminal Methyltransferase 1 Using Bisubstrate Analogs
  af: Chen, Dongxing, et al.
  Udgivet: (2020)