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Ubiquitin ligases in cancer: functions and clinical potentials
Ubiquitylation, a highly regulated post-translational modification, controls many cellular pathways that are critical to cell homeostasis. Ubiquitin ligases recruit substrates and promote ubiquitin transfer onto targets, inducing proteasomal degradation or non-degradative signaling. Accumulating evi...
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| Izdano u: | Cell Chem Biol |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8286310/ https://ncbi.nlm.nih.gov/pubmed/33974914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2021.04.008 |
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