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Tumor-draining lymph nodes are survival niches that support T cell priming against lymphatic transported tumor antigen and effects of immune checkpoint blockade in TNBC
Triple negative breast cancer (TNBC) is a significant clinical problem to which immunotherapeutic strategies have been applied with limited success. Using the syngeneic E0771 TNBC mouse model, this work explores the potential for antitumor CD8(+) T cell immunity to be primed extratumorally in lympho...
Gorde:
| Argitaratua izan da: | Cancer Immunol Immunother |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Springer Berlin Heidelberg
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8286278/ https://ncbi.nlm.nih.gov/pubmed/33459842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02792-5 |
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