HIV Protein Tat Induces Macrophage Dysfunction and Atherosclerosis Development in Low-Density Lipoprotein Receptor-Deficient Mice

PURPOSE: HIV infection is consistently associated with an increased risk of atherosclerotic cardiovascular disease, but the underlying mechanisms remain elusive. HIV protein Tat, a transcriptional activator of HIV, has been shown to activate NF-κB signaling and promote inflammation in vitro. However...

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Pubblicato in:Cardiovasc Drugs Ther
Autori principali: Meng, Zhaojie, Hernandez, Rebecca, Liu, Jingwei, Gwag, Taesik, Lu, Weiwei, Hsiai, Tzung K, Kaul, Marcus, Zhou, Tong, Zhou, Changcheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2022
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286272/
https://ncbi.nlm.nih.gov/pubmed/33459922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-021-07141-x
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