The role of the HIF‐1α/ALYREF/PKM2 axis in glycolysis and tumorigenesis of bladder cancer

BACKGROUND: As a rate‐limiting enzyme of glycolysis, pyruvate kinase muscle isozyme M2 (PKM2) participates in tumor metabolism and growth. The regulatory network of PKM2 in cancer is complex and has not been fully studied in bladder cancer. The 5‐methylcytidine (m5C) modification in PKM2 mRNA might...

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Detalhes bibliográficos
Publicado no:Cancer Commun (Lond)
Main Authors: Wang, Jing‐Zi, Zhu, Wei, Han, Jie, Yang, Xiao, Zhou, Rui, Lu, Hong‐Cheng, Yu, Hao, Yuan, Wen‐Bo, Li, Peng‐Chao, Tao, Jun, Lu, Qiang, Wei, Ji‐Fu, Yang, Haiwei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286140/
https://ncbi.nlm.nih.gov/pubmed/33991457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cac2.12158
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