Bidirectional flow of the funny current (I(f)) during the pacemaking cycle in murine sinoatrial node myocytes

Sinoatrial node myocytes (SAMs) act as cardiac pacemaker cells by firing spontaneous action potentials (APs) that initiate each heartbeat. The funny current (I(f)) is critical for the generation of these spontaneous APs; however, its precise role during the pacemaking cycle remains unresolved. Here,...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Peters, Colin H., Liu, Pin W., Morotti, Stefano, Gantz, Stephanie C., Grandi, Eleonora, Bean, Bruce P., Proenza, Catherine
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285948/
https://ncbi.nlm.nih.gov/pubmed/34260402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2104668118
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