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Calcium channel blockers do not protect against saturated fatty acid-induced ER stress and apoptosis in human pancreatic β-cells

It was evidenced that saturated fatty acids (FAs) have a detrimental effect on pancreatic β-cells function and survival, leading to endoplasmic reticulum (ER) calcium release, ER stress, and apoptosis. In the present study, we have tested the effect of three calcium influx inhibitors, i.e., diazoxid...

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Foilsithe in:Nutr Metab (Lond)
Main Authors: Šrámek, Jan, Němcová, Vlasta, Kovář, Jan
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285784/
https://ncbi.nlm.nih.gov/pubmed/34274001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-021-00597-6
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