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Calcium channel blockers do not protect against saturated fatty acid-induced ER stress and apoptosis in human pancreatic β-cells

It was evidenced that saturated fatty acids (FAs) have a detrimental effect on pancreatic β-cells function and survival, leading to endoplasmic reticulum (ER) calcium release, ER stress, and apoptosis. In the present study, we have tested the effect of three calcium influx inhibitors, i.e., diazoxid...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nutr Metab (Lond)
Päätekijät: Šrámek, Jan, Němcová, Vlasta, Kovář, Jan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285784/
https://ncbi.nlm.nih.gov/pubmed/34274001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-021-00597-6
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