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Calcium channel blockers do not protect against saturated fatty acid-induced ER stress and apoptosis in human pancreatic β-cells

It was evidenced that saturated fatty acids (FAs) have a detrimental effect on pancreatic β-cells function and survival, leading to endoplasmic reticulum (ER) calcium release, ER stress, and apoptosis. In the present study, we have tested the effect of three calcium influx inhibitors, i.e., diazoxid...

詳細記述

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書誌詳細
出版年:Nutr Metab (Lond)
主要な著者: Šrámek, Jan, Němcová, Vlasta, Kovář, Jan
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285784/
https://ncbi.nlm.nih.gov/pubmed/34274001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-021-00597-6
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