Ablation of Sam68 in adult mice increases thermogenesis and energy expenditure

Genetic deletion of Sam68, a pleiotropic adaptor protein prevents high-fat-diet–induced weight gain and insulin resistance. To clarify the role of Sam68 in energy metabolism in the adult stage, we generated an inducible Sam68 knockout mice. Knockout of Sam68 was induced at the age of 7-10 weeks, and...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Qiao, Aijun, Ma, Wenxia, Deng, Jianxin, Zhou, Junlan, Han, Chaoshan, Zhang, Eric, Boriboun, Chan, Xu, Shiyue, Zhang, Chunxiang, Jie, Chunfa, Kim, Jeong-a, Habegger, Kirk, Qiu, Hongyu, Zhao, Ting C, Zhang, Jianyi, Qin, Gangjian
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285032/
https://ncbi.nlm.nih.gov/pubmed/34252225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202100021R
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