Anticancer Activity and In Vitro to In Vivo Mechanistic Recapitulation of Novel Ruthenium-Based Metallodrugs in the Zebrafish Model

Ruthenium is popular as a metal core for chemotherapeutics, due to versatile molecular coordination. Because new metallodrugs are synthesized at high rates, our studies included assays in zebrafish to expedite the initial evaluation as anticancer agents. Here we evaluated novel metallodrugs (PMC79 a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Toxicol Sci
Main Authors: Karas, Brittany F, Hotz, Jordan M, Gural, Brian M, Terez, Kristin R, DiBona, Victoria L, Côrte-Real, Leonor, Valente, Andreia, Buckley, Brian T, Cooper, Keith R
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
Clinical and Translational Toxicology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285015/
https://ncbi.nlm.nih.gov/pubmed/33822233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfab041
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