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Ruthenium versus Platinum: Interactions of Anticancer Metallodrugs with Duplex Oligonucleotides Characterised by Electrospray Ionisation-Mass Spectrometry

The binding of the ruthenium-based anticancer drug candidates KP1019, NAMI-A, and RAPTA-T towards different double-stranded oligonucleotides was probed by electrospray ionisation-mass spectrometry (ESI-MS) and compared to the widely used platinum-based chemotherapeutics cisplatin, carboplatin and ox...

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Detalhes bibliográficos
Publicado no:J Biol Inorg Chem
Main Authors: Groessl, Michael, Tsybin, Yury O., Hartinger, Christian G., Keppler, Bernhard K., Dyson, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485486/
https://ncbi.nlm.nih.gov/pubmed/20213306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-010-0635-0
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