Transferring the Concept of Multinuclearity to Ruthenium Complexes for Improvement of Anticancer Activity

Multinuclear platinum anticancer complexes are a proven option to overcome resistance of established anticancer compounds. Transferring this concept to ruthenium complexes led to the synthesis of dinuclear Ru(II)–arene compounds containing a bis(pyridinone)alkane ligand linker. A pronounced influenc...

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Detalhes bibliográficos
Main Authors: Mendoza-Ferri, Maria G., Hartinger, Christian G., Mendoza, Marco A., Groessl, Michael, Egger, Alexander E., Eichinger, Rene E., Mangrum, John B., Farrell, Nicholas P., Maruszak, Magdalena, Bednarski, Patrick J., Klein, Franz, Jakupec, Michael A., Nazarov, Alexey A., Severin, Kay, Keppler, Bernhard K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819033/
https://ncbi.nlm.nih.gov/pubmed/19170599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8013234
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