Transferring the Concept of Multinuclearity to Ruthenium Complexes for Improvement of Anticancer Activity

Multinuclear platinum anticancer complexes are a proven option to overcome resistance of established anticancer compounds. Transferring this concept to ruthenium complexes led to the synthesis of dinuclear Ru(II)–arene compounds containing a bis(pyridinone)alkane ligand linker. A pronounced influenc...

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Main Authors: Mendoza-Ferri, Maria G., Hartinger, Christian G., Mendoza, Marco A., Groessl, Michael, Egger, Alexander E., Eichinger, Rene E., Mangrum, John B., Farrell, Nicholas P., Maruszak, Magdalena, Bednarski, Patrick J., Klein, Franz, Jakupec, Michael A., Nazarov, Alexey A., Severin, Kay, Keppler, Bernhard K.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819033/
https://ncbi.nlm.nih.gov/pubmed/19170599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8013234
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