Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells

Black cohosh extract (BCE) is marketed to women as an alternative to hormone replacement therapy for alleviating menopausal symptoms. Previous studies by the National Toxicology Program revealed that BCE induced micronuclei (MN) and a nonregenerative macrocytic anemia in rats and mice, likely caused...

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Dettagli Bibliografici
Pubblicato in:Toxicol Sci
Autori principali: Seo, Ji-Eun, Guo, Xiaoqing, Petibone, Dayton M, Shelton, Sharon D, Chen, Ying, Li, Xilin, Tryndyak, Volodymyr, Smith-Roe, Stephanie L, Witt, Kristine L, Mei, Nan, Manjanatha, Mugimane G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
Genetic and Epigenetic Toxicology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285013/
https://ncbi.nlm.nih.gov/pubmed/33856461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfab044
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