Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells

Black cohosh extract (BCE) is marketed to women as an alternative to hormone replacement therapy for alleviating menopausal symptoms. Previous studies by the National Toxicology Program revealed that BCE induced micronuclei (MN) and a nonregenerative macrocytic anemia in rats and mice, likely caused...

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Vydáno v:Toxicol Sci
Hlavní autoři: Seo, Ji-Eun, Guo, Xiaoqing, Petibone, Dayton M, Shelton, Sharon D, Chen, Ying, Li, Xilin, Tryndyak, Volodymyr, Smith-Roe, Stephanie L, Witt, Kristine L, Mei, Nan, Manjanatha, Mugimane G
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Genetic and Epigenetic Toxicology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285013/
https://ncbi.nlm.nih.gov/pubmed/33856461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfab044
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