Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells

Black cohosh extract (BCE) is marketed to women as an alternative to hormone replacement therapy for alleviating menopausal symptoms. Previous studies by the National Toxicology Program revealed that BCE induced micronuclei (MN) and a nonregenerative macrocytic anemia in rats and mice, likely caused...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Seo, Ji-Eun, Guo, Xiaoqing, Petibone, Dayton M, Shelton, Sharon D, Chen, Ying, Li, Xilin, Tryndyak, Volodymyr, Smith-Roe, Stephanie L, Witt, Kristine L, Mei, Nan, Manjanatha, Mugimane G
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Genetic and Epigenetic Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285013/
https://ncbi.nlm.nih.gov/pubmed/33856461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfab044
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