Co-existence of a novel plasmid-mediated efflux pump with colistin resistance gene mcr in one plasmid confers transferable multidrug resistance in Klebsiella pneumoniae

Tigecycline is considered one of the last-resort antimicrobials for carbapenem-resistant K. pneumoniae. Plasmid-mediated tigecycline resistance remains largely unclear. Here, by utilizing whole genome sequencing, we report a plasmid-mediated tigecycline resistance mechanism, a 6,489 bp Resistance-no...

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Udgivet i:Emerg Microbes Infect
Main Authors: Sun, Shijun, Gao, Hua, Liu, Yudong, Jin, Longyang, Wang, Ruobing, Wang, Xiaojuan, Wang, Qi, Yin, Yuyao, Zhang, Yawei, Wang, Hui
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284978/
https://ncbi.nlm.nih.gov/pubmed/32401163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2020.1768805
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