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Effects of Efflux Pump Inhibitors on Colistin Resistance in Multidrug-Resistant Gram-Negative Bacteria

We tested the effects of various putative efflux pump inhibitors on colistin resistance in multidrug-resistant Gram-negative bacteria. Addition of 10 mg/liter cyanide 3-chlorophenylhydrazone (CCCP) to the test medium could significantly decrease the MICs of colistin-resistant strains. Time-kill assa...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ni, Wentao, Li, Yanjun, Guan, Jie, Zhao, Jin, Cui, Junchang, Wang, Rui, Liu, Youning
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862505/
https://ncbi.nlm.nih.gov/pubmed/26953203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00248-16
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