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Immune Checkpoint Inhibition is Safe and Effective for Liver Cancer Prevention in a Mouse Model of Hepatocellular Carcinoma

Cirrhosis is a high-risk state for hepatocellular carcinoma (HCC) development and represents an opportunity to prevent cancer. In the pre-cancerous state of cirrhosis, there is an accumulation of neoantigens that may be specifically targetable through immunotherapy. We asked if immune checkpoint inh...

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Bibliografiska uppgifter
I publikationen:Cancer Prev Res (Phila)
Huvudupphovsmän: Chung, Andrew S, Mettlen, Marcel, Ganguly, Debolina, Lu, Tianshi, Wang, Tao, Brekken, Rolf A, Hsiehchen, David, Zhu, Hao
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284815/
https://ncbi.nlm.nih.gov/pubmed/32839204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-20-0200
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