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Sitravatinib potentiates immune checkpoint blockade in refractory cancer models

Immune checkpoint blockade has achieved significant therapeutic success for a subset of cancer patients; however, a large portion of cancer patients do not respond. Unresponsive tumors are characterized as being immunologically “cold,” indicating that these tumors lack tumor antigen-specific primed...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Du, Wenting, Huang, Huocong, Sorrelle, Noah, Brekken, Rolf A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238734/
https://ncbi.nlm.nih.gov/pubmed/30385724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124184
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